azilsartan medoxomil

Ligand id: 6900

Name: azilsartan medoxomil

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 139.24
Molecular weight 569.17
XLogP 8.09
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (2011))
Is prodrug? Yes
Active form azilsartan
IUPAC Name
(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-ethoxy-3-[[4-[2-(5-oxo-2H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate
International Nonproprietary Names
INN number INN
8874 azilsartan medoxomil
Synonyms
Edarbi®
TAK 491
Database Links
CAS Registry No. 863031-21-4 (source: Scifinder)
ChEMBL Ligand CHEMBL2028661
DrugBank Ligand DB08822
PubChem CID 11238823
Search Google for chemical match using the InChIKey QJFSABGVXDWMIW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone QJFSABGVXDWMIW
Search PubMed clinical trials azilsartan medoxomil
Search PubMed titles azilsartan medoxomil
Search PubMed titles/abstracts azilsartan medoxomil
Wikipedia Azilsartan
Comments
Azilsartan medoxomil is metabolised into the active form azilsartan. The azilsartan ligand page (accessed via the link above) contains more details of the drug's clinical use and mechanistic action.
The marketed brand, Edarbi®, contains azilsartan medoxomil potassium (PubChem CID 23699544).