dextromethorphan

Ligand id: 6953

Name: dextromethorphan

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View more information in the IUPHAR Pharmacology Education Project: dextromethorphan

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 12.47
Molecular weight 271.19
XLogP 4.21
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (no history prior to 1982))
International Nonproprietary Names
INN number INN
166 dextromethorphan
Synonyms
d-methorphan
Comments
Dextromethorphan is a morphinan class sedative. It is available over-the-counter (OTC) for use as an antitussive. At doses much higher than medically recommended, dextromethorphan is used recreationally for its dissociative anesthetic and euphoria producing effects.
Database Links
CAS Registry No. 125-71-3
ChEMBL Ligand CHEMBL52440
DrugBank Ligand DB00514
GtoPdb PubChem SID 178103535
PubChem CID 5360696
Search Google for chemical match using the InChIKey MKXZASYAUGDDCJ-NJAFHUGGSA-N
Search Google for chemicals with the same backbone MKXZASYAUGDDCJ
Search PubMed clinical trials dextromethorphan
Search PubMed titles dextromethorphan
Search PubMed titles/abstracts dextromethorphan
Search UniChem for chemical match using the InChIKey MKXZASYAUGDDCJ-NJAFHUGGSA-N
Search UniChem for chemicals with the same backbone MKXZASYAUGDDCJ
Wikipedia Dextromethorphan