tazemetostat

Ligand id: 7011

Name: tazemetostat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 83.14
Molecular weight 572.34
XLogP 5.65
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-3-[ethyl(oxan-4-yl)amino]-2-methyl-5-[4-(morpholin-4-ylmethyl)phenyl]benzamide
International Nonproprietary Names
INN number INN
9963 tazemetostat
Synonyms
E-7438 | EPZ 6438 | EPZ-6438 | EPZ6438
Database Links
CAS Registry No. 1403254-99-8
PubChem CID 66558664
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Comments
Tazemetostat is an inhibitor of the histone methyltransferase, enhancer of zeste 2 polycomb repressive complex 2 subunit (EZH2), and is being investigated for its antineoplastic activity.