clobetasol propionate

Ligand id: 7062

Name: clobetasol propionate

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 80.67
Molecular weight 466.19
XLogP 2.98
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Metabolite or derivative
Approved drug? Yes (source: FDA (1985))
IUPAC Name
[(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
International Nonproprietary Names
INN number INN
3154 clobetasol
Synonyms
CCI-4725
Clobex®
Dermovate®
GR 2/925
Temovate®
Database Links
CAS Registry No. 25122-46-7
ChEMBL Ligand CHEMBL1159650
DrugBank Ligand DB01013
PubChem CID 32798
Search Google for chemical match using the InChIKey CBGUOGMQLZIXBE-XGQKBEPLSA-N
Search Google for chemicals with the same backbone CBGUOGMQLZIXBE
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Wikipedia Clobetasol propionate
Comments
Clobetasol is a highly active, topical corticosteroid.