Classification
Compound class	Synthetic organic
Approved drug?	Yes (source: FDA (1956))

IUPAC Name

2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)ethan-1-ol

International Nonproprietary Names
INN number	INN
599	hydroxyzine

Synonyms

Atarax®

hydroxyzine hydrochloride

hydroxyzine pamoate

Vistaril®

Database Links
CAS Registry No.	68-88-2
ChEMBL Ligand	CHEMBL896
DrugBank Ligand	DB00557
PubChem CID	3658
Search Google for chemical match using the InChIKey	ZQDWXGKKHFNSQK-UHFFFAOYSA-N
Search Google for chemicals with the same backbone	ZQDWXGKKHFNSQK
Search PubMed clinical trials	hydroxyzine
Search PubMed titles	hydroxyzine
Search PubMed titles/abstracts	hydroxyzine
Wikipedia	Hydroxyzine

Comments

Hydroxyzine is a first-generation diphenylmethane and piperazine class antihistamine. Second-generation antihistamine cetirizine is one of the metabolites of hydroxyzine, but cetirizine differs in that it appears not to cross the blood-brain barrier to any significant level.