tizanidine   Click here for help

GtoPdb Ligand ID: 7308

Synonyms: AN-021 | DS-103-282 | Zanaflex®
Approved drug
tizanidine is an approved drug (FDA (1996))
Compound class: Synthetic organic
Comment: Tizanidine is a centrally acting α2-adrenoceptor agonist.
Marketed formulations may contain tizanidine hydrochloride (PubChem CID 114869).
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 90.44
Molecular weight 253.02
XLogP 2.25
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES Clc1ccc2c(c1NC1=NCCN1)nsn2
Isomeric SMILES Clc1ccc2c(c1NC1=NCCN1)nsn2
InChI InChI=1S/C9H8ClN5S/c10-5-1-2-6-8(15-16-14-6)7(5)13-9-11-3-4-12-9/h1-2H,3-4H2,(H2,11,12,13)
InChI Key XFYDIVBRZNQMJC-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1996))
IUPAC Name Click here for help
5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine
International Nonproprietary Names Click here for help
INN number INN
4697 tizanidine
Synonyms Click here for help
AN-021 | DS-103-282 | Zanaflex®
Database Links Click here for help
Specialist databases
GPCRdb Ligand tizanidine
Other databases
CAS Registry No. 51322-75-9
ChEMBL Ligand CHEMBL1079
DrugBank Ligand DB00697
DrugCentral Ligand 2683
GtoPdb PubChem SID 178103881
PubChem CID 5487
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UniChem Compound Search for chemical match using the InChIKey XFYDIVBRZNQMJC-UHFFFAOYSA-N
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Wikipedia Tizanidine