oliceridine

Ligand id: 7334

Name: oliceridine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 71.62
Molecular weight 386.2
XLogP 4.37
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
[(3-methoxythiophen-2-yl)methyl]({2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]ethyl})amine
International Nonproprietary Names
INN number INN
10250 oliceridine
Synonyms
TRV130 | TRV130A
Database Links
ChEMBL Ligand CHEMBL2443262
PubChem CID 66553195
Search Google for chemical match using the InChIKey DMNOVGJWPASQDL-OAQYLSRUSA-N
Search Google for chemicals with the same backbone DMNOVGJWPASQDL
Search PubMed clinical trials oliceridine
Search PubMed titles oliceridine
Search PubMed titles/abstracts oliceridine
Search UniChem for chemical match using the InChIKey DMNOVGJWPASQDL-OAQYLSRUSA-N
Search UniChem for chemicals with the same backbone DMNOVGJWPASQDL
Wikipedia TRV130
Comments
Oliceridine (TRV130) is an opioid compound. This compound has been developed to exhibit biased-signalling, with the aim of reducing the adverse effects associated with use of other opioid drugs [1-2].