Structure and Physico-chemical Properties
|
Molecular properties generated using the CDK |
|||||||||||||||||||
Classification  |
|
| Compound class | Synthetic organic |
| IUPAC Name |
| ethyl 5-cyano-2-methyl-6-[4-(phenylmethylsulfonylcarbamoyl)piperidin-1-yl]pyridine-3-carboxylate |
| Synonyms |
| AZD 1283 | AZD-1283 |
| Comments |
| Antagonist of P2Y12 developed as non-nucleoside analogue alternative to marketed inhibitors such as ticagrelor [1,4]. An antiplatelet agent that is orally bioavailable and has improved drug-like properties was discovered through optimization of AZD1283 [3]. |
| Database Links |
|
| CAS Registry No. | 919351-41-0 (source: Scifinder) |
| ChEMBL Ligand | CHEMBL2419490 |
| GtoPdb PubChem SID | 178103932 |
| PubChem CID | 23649325 |
| RCSB PDB Ligand | AZJ |
| Search Google for chemical match using the InChIKey | NEMHKCNXXRQYRF-UHFFFAOYSA-N |
| Search Google for chemicals with the same backbone | NEMHKCNXXRQYRF |
| Search UniChem for chemical match using the InChIKey | NEMHKCNXXRQYRF-UHFFFAOYSA-N |
| Search UniChem for chemicals with the same backbone | NEMHKCNXXRQYRF |
Product suppliers
View disclaimer
Sponsored products disclaimer
Product supplier links are provided as a service to assist in identifying commercial suppliers of reagents that are mentioned on the IUPHAR/BPS Guide to PHARMACOLOGY database website, and do not imply their endorsement by NC-IUPHAR.
Links are provided in return for sponsorship, used to fund improvements to this database. The sponsorship account is managed and audited by the University of Edinburgh, a charitable body registered in Scotland, SC005336. If you are interested in sponsoring the database, please contact us.
✖
Sponsored products disclaimer
Product supplier links are provided as a service to assist in identifying commercial suppliers of reagents that are mentioned on the IUPHAR/BPS Guide to PHARMACOLOGY database website, and do not imply their endorsement by NC-IUPHAR.
Links are provided in return for sponsorship, used to fund improvements to this database. The sponsorship account is managed and audited by the University of Edinburgh, a charitable body registered in Scotland, SC005336. If you are interested in sponsoring the database, please contact us.
✖
AZD 1283
Cat. No. 6085 |
