mipomersen

Ligand id: 7364

Name: mipomersen

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 160
Hydrogen bond donors 26
Rotatable bonds 156
Topological polar surface area 3334.68
Molecular weight 7152.94
XLogP -19.15
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2013))
International Nonproprietary Names
INN number INN
8946 mipomersen
Synonyms
ISIS 301012 parent acid | Kynamro®
Comments
MOE in the nucleotide image denotes nucleosides with 2'-O-(2-methoxyethyl) modification. The drug formulation contains the sodium salt, mipomersen sodium (CHEMBL2107849).
Database Links
CAS Registry No. 1000120-98-8 (source: Scifinder)
ChEMBL Ligand CHEMBL2219536
DrugBank Ligand DB05528
GtoPdb PubChem SID 178103936
PubChem CID 71301230
Search Google for chemical match using the InChIKey TZRFSLHOCZEXCC-HIVFKXHNSA-A
Search Google for chemicals with the same backbone TZRFSLHOCZEXCC
Search PubMed clinical trials mipomersen
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Search UniChem for chemical match using the InChIKey TZRFSLHOCZEXCC-HIVFKXHNSA-A
Search UniChem for chemicals with the same backbone TZRFSLHOCZEXCC
Wikipedia Mipomersen