dosulepin

Ligand id: 7549

Name: dosulepin

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 28.54
Molecular weight 295.14
XLogP 5.85
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name
(3Z)-3-(6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethylpropan-1-amine
International Nonproprietary Names
INN number INN
1790 dosulepin
Synonyms
Dothep® | dothiepin | Prothiaden®
Database Links
CAS Registry No. 113-53-1
ChEBI CHEBI:36802
ChEMBL Ligand CHEMBL108947
GtoPdb PubChem SID 223365885
PubChem CID 5282426
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Wikipedia Dosulepin
Comments
Dosulepin is a tricyclic antidepressant. Functionally it acts as a serotonin-norepinephrine reuptake inhibitor (SNRI) with anticholinergic, antihistamine, and antiadrenergic effects.