lofepramine

Ligand id: 7551

Name: lofepramine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 7
Topological polar surface area 23.55
Molecular weight 418.18
XLogP 7.1
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
Withdrawn drug? Yes
IUPAC Name
1-(4-chlorophenyl)-2-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methylamino]ethanone
International Nonproprietary Names
INN number INN
2909 lofepramine
Synonyms
Gamanil ® | Lomont ® | WHR-2908A
Database Links
CAS Registry No. 23047-25-8
ChEBI CHEBI:47782
ChEMBL Ligand CHEMBL87708
GtoPdb PubChem SID 223365887
PubChem CID 3947
Search Google for chemical match using the InChIKey SAPNXPWPAUFAJU-UHFFFAOYSA-N
Search Google for chemicals with the same backbone SAPNXPWPAUFAJU
Search PubMed clinical trials lofepramine
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Search PubMed titles/abstracts lofepramine
Search UniChem for chemical match using the InChIKey SAPNXPWPAUFAJU-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone SAPNXPWPAUFAJU
Wikipedia Lofepramine
Comments
Marketed formulations may contain lofepramine hydrochloride (PubChem CID 33611).