AZD1332

Ligand id: 7700

Name: AZD1332

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 7
Topological polar surface area 100.64
Molecular weight 391.13
XLogP 3.56
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
5-chloro-2-N-[1-(5-fluoropyridin-2-yl)ethyl]-4-N-(3-propan-2-yloxy-1H-pyrazol-5-yl)pyrimidine-2,4-diamine
Synonyms
AZD 1332 | AZD-1332
Comments
AZD1332 is an inhibitor of neurotrophic tyrosine kinase receptors trkA, B and C (aka neurotrophic tyrosine kinase, receptor, type 1, 2 and 3). This compound is included in AstaZeneca's Open Innovation Pharmacology Toolbox.
Database Links
ChEMBL Ligand CHEMBL2007421
GtoPdb PubChem SID 223366033
PubChem CID 49831044
Search Google for chemical match using the InChIKey LBVKEEFIPBQIMD-UHFFFAOYSA-N
Search Google for chemicals with the same backbone LBVKEEFIPBQIMD
Search UniChem for chemical match using the InChIKey LBVKEEFIPBQIMD-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone LBVKEEFIPBQIMD