lesogaberan

Ligand id: 7705

Name: lesogaberan

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 86.79
Molecular weight 141.04
XLogP -1.12
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
[(2R)-3-amino-2-fluoropropyl]phosphinic acid
International Nonproprietary Names
INN number INN
9048 lesogaberan
Synonyms
AZD-3355 | AZD3355
Database Links
CAS Registry No. 344413-67-8
ChEMBL Ligand CHEMBL448343
PubChem CID 16686147
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Wikipedia Lesogaberan
Comments
Lesogaberan is an agonist of gamma-aminobutyric acid receptor B (GABAB). This was an investigational compound tested for potential to treat gastroesophageal reflux disease (GERD). This compound is now included in AstaZeneca's Open Innovation Pharmacology Toolbox.