lesogaberan

Ligand id: 7705

Name: lesogaberan

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 86.79
Molecular weight 141.04
XLogP -1.12
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
[(2R)-3-amino-2-fluoropropyl]phosphinic acid
International Nonproprietary Names
INN number INN
9048 lesogaberan
Synonyms
AZD-3355 | AZD3355
Comments
Lesogaberan is an agonist of gamma-aminobutyric acid receptor B (GABAB). This was an investigational compound tested for potential to treat gastroesophageal reflux disease (GERD). This compound is now included in AstaZeneca's Open Innovation Pharmacology Toolbox.
Database Links
CAS Registry No. 344413-67-8
ChEMBL Ligand CHEMBL448343
GtoPdb PubChem SID 223366038
PubChem CID 16686147
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Wikipedia Lesogaberan