AZD6495

Ligand id: 7711

Name: AZD6495

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 83.72
Molecular weight 441.2
XLogP 2.59
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-[(2,4-difluorophenyl)amino]-7-ethoxy-6-(4-methylpiperazin-1-yl)quinoline-3-carboxamide
Synonyms
AZD 6495 | AZD-6495
Comments
AZD6495 is an investigational inhibitor of the colony stimulating factor-1 receptor (CSF-1R) tyrosine kinase [1]. It was developed as an antineoplastic agent. This compound is now included in AstaZeneca's Open Innovation Pharmacology Toolbox.
Database Links
ChEMBL Ligand CHEMBL481806
GtoPdb PubChem SID 223366044
PubChem CID 16755780
Search Google for chemical match using the InChIKey IBHNEKVLDKCEQY-UHFFFAOYSA-N
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Search UniChem for chemical match using the InChIKey IBHNEKVLDKCEQY-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone IBHNEKVLDKCEQY