AZD8329

Ligand id: 7715

Name: AZD8329

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 84.22
Molecular weight 421.24
XLogP 5.1
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-[4-(2-adamantylcarbamoyl)-5-tert-butylpyrazol-1-yl]benzoic acid
Synonyms
AZD 8329 | AZD-8329
Comments
AZD8329 is an inhibitor of 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1). This compound is included in AstaZeneca's Open Innovation Pharmacology Toolbox.
Database Links
ChEMBL Ligand CHEMBL2177609
GtoPdb PubChem SID 223366048
PubChem CID 25006684
Search Google for chemical match using the InChIKey XWBXJBSVYVJAMZ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone XWBXJBSVYVJAMZ
Search UniChem for chemical match using the InChIKey XWBXJBSVYVJAMZ-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone XWBXJBSVYVJAMZ