AZD8542

Ligand id: 7716

Name: AZD8542

2D Structure

Calculated Physico-chemical Properties
Hydrogen bond acceptors	5
Hydrogen bond donors	1
Rotatable bonds	7
Topological polar surface area	69.04
Molecular weight	412.19
XLogP	5.09
No. Lipinski's rules broken	1

Molecular properties generated using the CDK

Classification
Compound class	Synthetic organic

IUPAC Name
N-[2,4-dimethyl-5-(1-methylimidazol-4-yl)phenyl]-4-(pyridin-2-ylmethoxy)benzamide

IUPAC Name

N-[2,4-dimethyl-5-(1-methylimidazol-4-yl)phenyl]-4-(pyridin-2-ylmethoxy)benzamide

Synonyms
AZD 8542 \| AZD-8542

Synonyms

AZD 8542 | AZD-8542

Database Links
GtoPdb PubChem SID	223366049
PubChem CID	53344810
Search Google for chemical match using the InChIKey	SMQVBAGSZVHCJP-UHFFFAOYSA-N
Search Google for chemicals with the same backbone	SMQVBAGSZVHCJP
Search UniChem for chemical match using the InChIKey	SMQVBAGSZVHCJP-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone	SMQVBAGSZVHCJP

Comments
AZD8542 was developed as an antagonist of Smoothened (SMO), with potential as an oncology therapeutic [2]. This compound is now included in AstaZeneca's Open Innovation Pharmacology Toolbox.

Comments

AZD8542 was developed as an antagonist of Smoothened (SMO), with potential as an oncology therapeutic [2]. This compound is now included in AstaZeneca's Open Innovation Pharmacology Toolbox.