AZ12260493

Ligand id: 7725

Name: AZ12260493

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 78.1
Molecular weight 439.19
XLogP 6.35
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-tert-butyl-1,1-dioxo-5-phenyl-4-[(4-piperidin-1-ylphenyl)amino]-1,2-thiazol-3-one
Synonyms
AZ 12260493 | AZ-12260493
Comments
AZ12260493 was developed as an agonist of the liver X receptors α and β and investigated as a treatment for dyslipidaemia. This compound is now included in AstaZeneca's Open Innovation Pharmacology Toolbox.
Database Links
GtoPdb PubChem SID 223366058
PubChem CID 11655079
Search Google for chemical match using the InChIKey IVANYIPLGFVBGR-UHFFFAOYSA-N
Search Google for chemicals with the same backbone IVANYIPLGFVBGR
Search UniChem for chemical match using the InChIKey IVANYIPLGFVBGR-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone IVANYIPLGFVBGR