QNZ 46

Ligand id: 7845

Name: QNZ 46

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 122.11
Molecular weight 444.12
XLogP 4.64
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-[6-methoxy-2-[(E)-2-(3-nitrophenyl)ethenyl]-4-oxo-4aH-quinazolin-3-ium-3-yl]benzoic acid
Synonyms
KB-275239
Database Links
CAS Registry No. 1237744-13-6
PubChem CID 76850154
Search Google for chemical match using the InChIKey ZLXASDKCRPAANV-LFYBBSHMSA-O
Search Google for chemicals with the same backbone ZLXASDKCRPAANV
Search UniChem for chemical match using the InChIKey ZLXASDKCRPAANV-LFYBBSHMSA-O
Search UniChem for chemicals with the same backbone ZLXASDKCRPAANV
Comments
QNZ 46 is a negative allosteric modulator of the GluN2C/D NMDA receptor inhibiting receptor function more potently when glutamate (but not glycine) is present [1].