USP7/USP47 inhibitor

Ligand id: 7895

Name: USP7/USP47 inhibitor

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 161.84
Molecular weight 482.93
XLogP 2.49
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-cyano-5-(3,5-dichloropyridin-4-yl)sulfanyl-N-(4-methylsulfonylphenyl)thiophene-2-carboxamide
Synonyms
compound 14 [PMID: 24900381]
Database Links
PubChem CID 51031028
Search Google for chemical match using the InChIKey GUDJFFQZIISQJB-UHFFFAOYSA-N
Search Google for chemicals with the same backbone GUDJFFQZIISQJB
Search UniChem for chemical match using the InChIKey GUDJFFQZIISQJB-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone GUDJFFQZIISQJB
Comments
Selective dual Inhibitor of the cancer-related deubiquitylating proteases USP7 (Q93009) and USP47 (Q96K76) [1].