uprosertib

Ligand id: 7902

Name: uprosertib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 86.08
Molecular weight 428.06
XLogP 2.57
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[(2S)-1-amino-3-(3,4-difluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-2-methylpyrazol-3-yl)furan-2-carboxamide
International Nonproprietary Names
INN number INN
9942 uprosertib
Synonyms
GSK-2141795 | GSK2141795
Database Links
CAS Registry No. 1047634-65-0
ChEMBL Ligand CHEMBL3137336
PubChem CID 51042438
Search Google for chemical match using the InChIKey AXTAPYRUEKNRBA-JTQLQIEISA-N
Search Google for chemicals with the same backbone AXTAPYRUEKNRBA
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Search UniChem for chemical match using the InChIKey AXTAPYRUEKNRBA-JTQLQIEISA-N
Search UniChem for chemicals with the same backbone AXTAPYRUEKNRBA
Comments
Uprosertib (GSK-2141795) is an inhibitor of the AKT family of protein kinases [1].