MK-2206

Ligand id: 7945

Name: MK-2206

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 71.25
Molecular weight 407.17
XLogP 6.24
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-2H-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-one
Synonyms
MK 2206
Database Links
CAS Registry No. 1032350-13-2
ChEBI CHEBI:67271
ChEMBL Ligand CHEMBL1079175
PubChem CID 24964624
Search Google for chemical match using the InChIKey ULDXWLCXEDXJGE-UHFFFAOYSA-N
Search Google for chemicals with the same backbone ULDXWLCXEDXJGE
Search UniChem for chemical match using the InChIKey ULDXWLCXEDXJGE-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone ULDXWLCXEDXJGE
Comments
MK-2206 is an orally bioavailable allosteric inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity [2-4].