LY2090314

Ligand id: 7958

Name: LY2090314

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 91.95
Molecular weight 512.2
XLogP 2.48
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Synonyms
LY-2090314
Database Links
ChEMBL Ligand CHEMBL362558
PubChem CID 10029385
Search Google for chemical match using the InChIKey HRJWTAWVFDCTGO-UHFFFAOYSA-N
Search Google for chemicals with the same backbone HRJWTAWVFDCTGO
Search UniChem for chemical match using the InChIKey HRJWTAWVFDCTGO-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone HRJWTAWVFDCTGO
Comments
LY2090314 is a potent inhibitor of glycogen synthase kinase-3 (GSK3) [2,4]. The discovery of LY2090314 is described by Engler et al. (2004) [2] where it is compound 12.