GSK2636771

Ligand id: 7967

Name: GSK2636771

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 67.59
Molecular weight 433.16
XLogP 4.82
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-methyl-1-[[2-methyl-3-(trifluoromethyl)phenyl]methyl]-6-morpholin-4-ylbenzimidazole-4-carboxylic acid
Synonyms
GSK-2636771
Database Links
CAS Registry No. 1372540-25-4
ChEMBL Ligand CHEMBL3188551
PubChem CID 56949517
Search Google for chemical match using the InChIKey XTKLTGBKIDQGQL-UHFFFAOYSA-N
Search Google for chemicals with the same backbone XTKLTGBKIDQGQL
Search UniChem for chemical match using the InChIKey XTKLTGBKIDQGQL-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone XTKLTGBKIDQGQL
Comments
GSK2636771 is a potent, orally bioavailable, PI3Kβ-selective inhibitor, with anticancer effects in PTEN null cells [1].