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Molecular properties generated using the CDK |
Classification ![]() |
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Compound class | Synthetic organic |
IUPAC Name ![]() |
3-N-(1H-indol-5-yl)-5-pyridin-4-ylpyrazine-2,3-diamine |
Synonyms ![]() |
AKN 028 | AKN028 |
Database Links ![]() |
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CAS Registry No. | 1175017-90-9 |
GtoPdb PubChem SID | 249565652 |
PubChem CID | 44177328 |
Search Google for chemical match using the InChIKey | JLRIJKVMMZEKDF-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | JLRIJKVMMZEKDF |
Search UniChem for chemical match using the InChIKey | JLRIJKVMMZEKDF-UHFFFAOYSA-N |
Search UniChem for chemicals with the same backbone | JLRIJKVMMZEKDF |
Comments |
AKN-028 is an orally bioavailable protein tyrosine kinase inhibitor for FMS-related tyrosine kinase 3 (FLT3) and stem cell factor receptor (SCFR; KIT), with potential antineoplastic activity [1-2]. The compound inhibits wild-type and mutant FLT3 and KIT kinases. |