zotarolimus

Ligand id: 7974

Name: zotarolimus

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 17
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 218.8
Molecular weight 965.57
XLogP 4.55
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
International Nonproprietary Names
INN number INN
8644 zotarolimus
Synonyms
ABT 578 | ABT-578 | ABT578
Database Links
CAS Registry No. 221877-54-9
ChEMBL Ligand CHEMBL219410
PubChem CID 9876378
Search Google for chemical match using the InChIKey CGTADGCBEXYWNE-JUKNQOCSSA-N
Search Google for chemicals with the same backbone CGTADGCBEXYWNE
Search PubMed clinical trials zotarolimus
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Search UniChem for chemical match using the InChIKey CGTADGCBEXYWNE-JUKNQOCSSA-N
Search UniChem for chemicals with the same backbone CGTADGCBEXYWNE
Wikipedia Zotarolimus
Comments
Zotarolimus (ABT-578) is an analogue of rapamycin (sirolimus). This compound was developed to be used in intravascular stents designed to elute anti-proliferative agent for the prevention of coronary restenosis.