bavituximab

Ligand id: 8002

Name: bavituximab

Classification
Compound class Antibody
International Nonproprietary Names
INN number INN
8734 bavituximab
Synonyms
Tarvacin ch3G4
Database Links
Specialist databases
IMGT/mAb-DB 149
Other databases
Search PubMed clinical trials bavituximab
Search PubMed titles bavituximab
Search PubMed titles/abstracts bavituximab
Wikipedia Bavituximab
Comments
Bavituximab is the first monoclonal antibody directed against phosphatidylserine, and is being investigated as a antineoplastic agent. Bavituximab belongs to an emerging class of antibodies known as vascular targeting agents (VTAs) which bind selectively to antigens present on tumour vascular cells. Typical VTAs either recruit host effector cells to destroy the tumour or are coupled to agents such as toxins, anticoagulants or pro-apoptotic drugs that occlude or destroy tumour blood vessels [3].
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.