IM-12

Ligand id: 8017

Name: IM-12

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 65.2
Molecular weight 377.15
XLogP 4.9
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
3-[2-(4-fluorophenyl)ethylamino]-1-methyl-4-(2-methyl-1H-indol-3-yl)pyrrole-2,5-dione
Database Links
CAS Registry No. 1129669-05-1
ChEMBL Ligand CHEMBL1254896
PubChem CID 25209788
Search Google for chemical match using the InChIKey ZKJAZFUFPPSFCO-UHFFFAOYSA-N
Search Google for chemicals with the same backbone ZKJAZFUFPPSFCO
Search UniChem for chemical match using the InChIKey ZKJAZFUFPPSFCO-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone ZKJAZFUFPPSFCO
Comments
IM-12 is a selective inhibitor of glycogen synthase kinase-3β (GSK-3β) [8].