AZD3409

Ligand id: 8027

Name: AZD3409

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 17
Topological polar surface area 142.95
Molecular weight 574.24
XLogP 6.43
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
propan-2-yl (2S)-2-[1-[2-(2-fluoroethyl)-5-[[(2S,5S)-5-(pyridine-3-carbonylsulfanyl)pyrrolidin-2-yl]methylamino]phenyl]ethenylamino]-4-methylsulfanylbutanoate
Synonyms
AZD 3409 | AZD-3409
Comments
AZD3409 is an an orally active double prodrug, peptidomimetic type farnesyltransferase inhibitor (FTI). It is a double prodrug in that it has its thiol and carboxylate groups blocked to reduce toxicity.
Database Links
GtoPdb PubChem SID 249565707
PubChem CID 56603668
Search Google for chemical match using the InChIKey GIJNHMGFNKZBIR-URORMMCBSA-N
Search Google for chemicals with the same backbone GIJNHMGFNKZBIR
Search UniChem for chemical match using the InChIKey GIJNHMGFNKZBIR-URORMMCBSA-N
Search UniChem for chemicals with the same backbone GIJNHMGFNKZBIR