L-739,750

Ligand id: 8030

Name: L-739,750

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 4
Rotatable bonds 18
Topological polar surface area 195
Molecular weight 517.23
XLogP 1.71
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(2S)-2-[[(2S)-2-[(2S,3S)-2-[[(2R)-2-amino-3-sulfanylpropyl]amino]-3-methylpentoxy]-3-phenylpropanoyl]amino]-4-methylsulfonylbutanoic acid
Synonyms
L 739750
Database Links
CAS Registry No. 160141-08-2 (source: Scifinder)
PubChem CID 5287548
RCSB PDB Ligand 739
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Comments
The discovery of L-739,750 is described in [2]. L-739,750 is a peptidomimetic farnesyltransferase inhibitor (FTI). Experimentally the compound is administered as a methyl ester prodrug (L-739,749) [2].