GSK269962A

Ligand id: 8037

Name: GSK269962A

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 11
Topological polar surface area 155.68
Molecular weight 570.23
XLogP 3.16
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[5,4-d]pyridin-6-yl]oxyphenyl]-4-(2-morpholin-4-ylethoxy)benzamide
Synonyms
aminofurazanyl-azabenzimidazole 6n | GSK-269962A | GSK269962
Database Links
CAS Registry No. 850664-21-0
ChEMBL Ligand CHEMBL220241
PubChem CID 16095342
Search Google for chemical match using the InChIKey YOVNFNXUCOWYSG-UHFFFAOYSA-N
Search Google for chemicals with the same backbone YOVNFNXUCOWYSG
Search UniChem for chemical match using the InChIKey YOVNFNXUCOWYSG-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone YOVNFNXUCOWYSG
Comments
GSK269962A [1] is an inhibitor that can be used as a tool compound to study the activity of the AGC family protein kinases ROCK1 and ROCK2. GSK269962A has some off-target activity against the protein kinases MSK1 and RSK1.