KU-60019

Ligand id: 8041

Name: KU-60019

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 105.64
Molecular weight 547.21
XLogP 3.3
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-N-[5-(6-morpholin-4-yl-4-oxopyran-2-yl)-9H-thioxanthen-2-yl]acetamide
Database Links
CAS Registry No. 925701-49-1
ChEMBL Ligand CHEMBL2140173
PubChem CID 15953870
Search Google for chemical match using the InChIKey SCELLOWTHJGVIC-BGYRXZFFSA-N
Search Google for chemicals with the same backbone SCELLOWTHJGVIC
Search UniChem for chemical match using the InChIKey SCELLOWTHJGVIC-BGYRXZFFSA-N
Search UniChem for chemicals with the same backbone SCELLOWTHJGVIC
Comments
KU-60019 [1] is an inhibitor that can be used as a tool compound to study the activity of the atypical protein kinase ATM. Known off-target inhibition has been determined for the β, γ and δ PI3 kinases.