PF-477736

Ligand id: 8043

Name: PF-477736

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 4
Rotatable bonds 5
Topological polar surface area 114.07
Molecular weight 419.21
XLogP 2.07
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Synonyms
PF 477736 | PF-00477736
Database Links
CAS Registry No. 952021-60-2
PubChem CID 16750408
Search Google for chemical match using the InChIKey YFNWWNRZJGMDBR-LJQANCHMSA-N
Search Google for chemicals with the same backbone YFNWWNRZJGMDBR
Search UniChem for chemical match using the InChIKey YFNWWNRZJGMDBR-LJQANCHMSA-N
Search UniChem for chemicals with the same backbone YFNWWNRZJGMDBR
Comments
PF-477736 [1] is an inhibitor that can be used as a tool compound to study the activity of the CAMK family protein kinase CHK1. Secondary, off-targets include VEGFR2, FMS and YES protein kinases.