SCH772984

Ligand id: 8056

Name: SCH772984

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 11
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 123.24
Molecular weight 587.28
XLogP 3.28
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(3R)-1-[2-oxo-2-[4-(4-pyrimidin-2-ylphenyl)piperazin-1-yl]ethyl]-N-(3-pyridin-4-yl-1H-indazol-5-yl)pyrrolidine-3-carboxamide
Synonyms
SCH-772984
Database Links
CAS Registry No. 942183-80-4
PubChem CID 24866313
RCSB PDB Ligand 38Z
Search Google for chemical match using the InChIKey HDAJDNHIBCDLQF-RUZDIDTESA-N
Search Google for chemicals with the same backbone HDAJDNHIBCDLQF
Search UniChem for chemical match using the InChIKey HDAJDNHIBCDLQF-RUZDIDTESA-N
Search UniChem for chemicals with the same backbone HDAJDNHIBCDLQF
SynPHARM 81089 (in complex with mitogen-activated protein kinase 1)
81090 (in complex with mitogen-activated protein kinase 1)
Comments
SCH772984 is an investigational inhibitor of the mitogen-activated protein kinases ERK1 and ERK2 [1].