GNF-5

Ligand id: 8065

Name: GNF-5

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 9
Topological polar surface area 96.37
Molecular weight 418.13
XLogP 4.35
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-(2-hydroxyethyl)-3-[6-[4-(trifluoromethoxy)anilino]pyrimidin-4-yl]benzamide
Synonyms
GNF 5 | GNF5
Database Links
CAS Registry No. 778277-15-9
ChEMBL Ligand CHEMBL1257423
PubChem CID 44129660
Search Google for chemical match using the InChIKey IIQUYGWWHIHOCF-UHFFFAOYSA-N
Search Google for chemicals with the same backbone IIQUYGWWHIHOCF
Search UniChem for chemical match using the InChIKey IIQUYGWWHIHOCF-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone IIQUYGWWHIHOCF
Comments
GNF-5 is an investigational selective and allosteric BCR-ABL inhibitor [2]. GNF-5 is a pharmacokinetically optimised analogue of GNF-2 (PubChem CID 5311510) [1].