NVP-AEW541

Ligand id: 8067

Name: NVP-AEW541

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 69.2
Molecular weight 439.24
XLogP 5.54
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
7-[3-(azetidin-1-ylmethyl)cyclobutyl]-5-[3-(phenylmethoxy)phenyl]pyrrolo[3,2-e]pyrimidin-4-amine
Synonyms
AEW541 | NVP AEW541 | NVP-AEW 541 | NVP-AEW541-A
Database Links
CAS Registry No. 475489-16-8
ChEMBL Ligand CHEMBL3188172
PubChem CID 11476171
Search Google for chemical match using the InChIKey AECDBHGVIIRMOI-UHFFFAOYSA-N
Search Google for chemicals with the same backbone AECDBHGVIIRMOI
Search UniChem for chemical match using the InChIKey AECDBHGVIIRMOI-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone AECDBHGVIIRMOI
Comments
NVP-AEW541 is a potent and selective inhibitor of the receptor tyrosine kinase, insulin-like growth factor I receptor (IGF1R) [1].