G749

Ligand id: 8108

Name: G749

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 91.41
Molecular weight 520.12
XLogP 4.94
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
8-bromo-2-[(1-methylpiperidin-4-yl)amino]-4-(4-phenoxyanilino)-6H-pyrido[4,3-d]pyrimidin-5-one
Synonyms
G-749
Database Links
CAS Registry No. 1457983-28-6
PubChem CID 78357765
Search Google for chemical match using the InChIKey SXWMIXPJPNCXQQ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone SXWMIXPJPNCXQQ
Search UniChem for chemical match using the InChIKey SXWMIXPJPNCXQQ-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone SXWMIXPJPNCXQQ
Comments
G-749 is a novel and potent inhibitor of wild type and mutant Fms-like tyrosine receptor kinase 3 (FLT3) [1].