GSK579289A

Ligand id: 8150

Name: GSK579289A

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 110.85
Molecular weight 510.15
XLogP 4.65
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
3-[(1R)-1-(2-chlorophenyl)ethoxy]-5-[6-(1-methylpiperidin-4-yl)oxybenzimidazol-1-yl]thiophene-2-carboxamide
Synonyms
compound 25 [PMID 19237286] | GSK-579289A
Database Links
ChEMBL Ligand CHEMBL1794070
PubChem CID 16051023
Search Google for chemical match using the InChIKey GILNGUYOGYOZMP-MRXNPFEDSA-N
Search Google for chemicals with the same backbone GILNGUYOGYOZMP
Search UniChem for chemical match using the InChIKey GILNGUYOGYOZMP-MRXNPFEDSA-N
Search UniChem for chemicals with the same backbone GILNGUYOGYOZMP
Comments
GSK579289A is an anlaogue assessed in a medicinal chemistry study to identify novel thiophene type inhibitors of polo-like kinase 1 (PLK1) [1].