indoximod

Ligand id: 8226

Name: indoximod

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 68.25
Molecular weight 218.11
XLogP -0.72
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(2R)-2-amino-3-(1-methylindol-3-yl)propanoic acid
International Nonproprietary Names
INN number INN
9896 indoximod
Synonyms
1-methyl-D-tryptophan | 1MT | D-1MT
Database Links
CAS Registry No. 110117-83-4
ChEMBL Ligand CHEMBL571209
PubChem CID 405012
Search Google for chemical match using the InChIKey ZADWXFSZEAPBJS-SNVBAGLBSA-N
Search Google for chemicals with the same backbone ZADWXFSZEAPBJS
Search PubMed clinical trials indoximod
Search PubMed titles indoximod
Search PubMed titles/abstracts indoximod
Search UniChem for chemical match using the InChIKey ZADWXFSZEAPBJS-SNVBAGLBSA-N
Search UniChem for chemicals with the same backbone ZADWXFSZEAPBJS
Comments
Indoximod is being investigated for its inhibitory action towards indoleamine 2,3-dioxygenase 1 (IDO1), a L-tryptophan degrading enzyme.