IOX2

Ligand id: 8229

Name: IOX2

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 106.94
Molecular weight 352.11
XLogP 4.25
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-[(1-benzyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]acetic acid
Synonyms
compound 6 [1]
Database Links
CAS Registry No. 931398-72-0
ChEMBL Ligand CHEMBL3186774
PubChem CID 54685215
Search Google for chemical match using the InChIKey CAOSCCRYLYQBES-UHFFFAOYSA-N
Search Google for chemicals with the same backbone CAOSCCRYLYQBES
Search UniChem for chemical match using the InChIKey CAOSCCRYLYQBES-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone CAOSCCRYLYQBES
Comments
IOX2 is a selective, cell permeable inhibitor of the hypoxia inducible factor (HIF) prolyl-hydroxylase protein PHD2. This is a compound from the Structural Genomics Consortium's (SGC) Epigenetics Probes Collection.