TGX-221

Ligand id: 8244

Name: TGX-221

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 44.81
Molecular weight 364.19
XLogP 3.31
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
7-methyl-2-morpholin-4-yl-9-[1-(phenylamino)ethyl]pyrido[2,1-b]pyrimidin-4-one
Synonyms
TGX 221
Database Links
CAS Registry No. 663619-89-4
ChEMBL Ligand CHEMBL1972466
PubChem CID 9907093
Search Google for chemical match using the InChIKey CPRAGQJXBLMUEL-UHFFFAOYSA-N
Search Google for chemicals with the same backbone CPRAGQJXBLMUEL
Search UniChem for chemical match using the InChIKey CPRAGQJXBLMUEL-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone CPRAGQJXBLMUEL
Comments
TGX-221 is reported as a selective inhibitor of phosphatidylinositol 3-kinase (PI3K) β [1].