ZM-306416

Ligand id: 8245

Name: ZM-306416

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 56.27
Molecular weight 333.07
XLogP 3.25
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine
Synonyms
CB-676475 | ZM 306416 | ZM306416
Database Links
CAS Registry No. 690206-97-4
ChEMBL Ligand CHEMBL150315
PubChem CID 5329006
Search Google for chemical match using the InChIKey YHUIUSRCUKUUQA-UHFFFAOYSA-N
Search Google for chemicals with the same backbone YHUIUSRCUKUUQA
Search UniChem for chemical match using the InChIKey YHUIUSRCUKUUQA-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone YHUIUSRCUKUUQA
Comments
ZM-306416 is reported as an inhibitor of VEGFR and EGFR [1]. Hennequin et al (1999) report selectivity for VEGFR2 (KDR) over VEGFR1 (Flt-1) [2] (ZM-306416 is compound 4 in [2]).