LDC1267

Ligand id: 8247

Name: LDC1267

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 96.73
Molecular weight 560.19
XLogP 5.31
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[4-(6,7-dimethoxyquinolin-4-yl)oxy-3-fluorophenyl]-4-ethoxy-1-(4-fluoro-2-methylphenyl)pyrazole-3-carboxamide
Database Links
CAS Registry No. 1361030-48-9
PubChem CID 56847486
Search Google for chemical match using the InChIKey ISPBCAXOSOLFME-UHFFFAOYSA-N
Search Google for chemicals with the same backbone ISPBCAXOSOLFME
Search UniChem for chemical match using the InChIKey ISPBCAXOSOLFME-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone ISPBCAXOSOLFME
Comments
LDC1267 is a selective inhibitor of TAM family kinases (Type XI receptor tyrosine kinases, TYRO3, Axl and MER) [1].