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Molecular properties generated using the CDK |
Classification ![]() |
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Compound class | Synthetic organic |
IUPAC Name ![]() |
4-(6-ethoxy-1-methoxythioxanthen-9-ylidene)-1-methylpiperidine |
Comments |
BF-1 is a selective antagonist of the 5-HT2B receptor, being investigated preclinically as an anti-migraine therapeutic [1]. Because this compound lacks high affinities for other monoamine receptors it should have fewer monoanimergic side effects than reported for previously used and withdrawn 5-HT2B antagonists such as methysergide and pizotifen. BF-1 is the result of structural modification of the chemical scaffold of methixene, a compound with high affinity for 5-HT2A, 2B, 2C, histamine H1, adrenaline α1A and muscarinic M2 receptors [1]. |
Database Links ![]() |
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CAS Registry No. | 518980-66-0 |
GtoPdb PubChem SID | 252166634 |
PubChem CID | 10287037 |
Search Google for chemical match using the InChIKey | ANZVBVKYXOGOQC-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | ANZVBVKYXOGOQC |
Search UniChem for chemical match using the InChIKey | ANZVBVKYXOGOQC-UHFFFAOYSA-N |
Search UniChem for chemicals with the same backbone | ANZVBVKYXOGOQC |