SKA-121

Ligand id: 8492

Name: SKA-121

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 52.05
Molecular weight 198.08
XLogP 3.34
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
5-methylnaphtho[2,1-d]oxazol-2-amine
Synonyms
SKA 121 | SKA121
Database Links
PubChem CID 91827362
Search Google for chemical match using the InChIKey JEGUERWMMMQFJV-UHFFFAOYSA-N
Search Google for chemicals with the same backbone JEGUERWMMMQFJV
Search UniChem for chemical match using the InChIKey JEGUERWMMMQFJV-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone JEGUERWMMMQFJV
Comments
SKA-121 has been shown to be a KCa3.1-specific positive gating modulator suitable for further exploring the therapeutic potential of KCa3.1 activation [1].