SB-633825

Ligand id: 8642

Name: SB-633825

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Topological polar surface area 82.46
Molecular weight 483.16
XLogP 6.3
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-[5-(6-methoxynaphthalen-2-yl)-1-methyl-2-(2-methyl-4-methylsulfonylphenyl)imidazol-4-yl]pyridine
Database Links
BindingDB Ligand 50221358
ChEMBL Ligand CHEMBL237571
PubChem CID 44433173
RCSB PDB Ligand R09
Search Google for chemical match using the InChIKey ZDSNJSQTPLXCSG-UHFFFAOYSA-N
Search Google for chemicals with the same backbone ZDSNJSQTPLXCSG
Search UniChem for chemical match using the InChIKey ZDSNJSQTPLXCSG-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone ZDSNJSQTPLXCSG
Comments
SB-633825 is a novel inhibitor of human serine/threonine kinase 10 (STK10). The crystal structure of SB-633825-bound STK10 has been deposited to the RSCB Protein Data Bank by the Structural Genomics Consortium (SGC- link here).