CGS-27023A

Ligand id: 8846

Name: CGS-27023A

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 117.21
Molecular weight 393.14
XLogP 1.86
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(2R)-N-hydroxy-2-[(4-methoxyphenyl)sulfonyl-(pyridin-3-ylmethyl)amino]-3-methylbutanamide
Synonyms
CGS 27023A | CGS27023A | MMI270
Comments
CGS-27023A is reported as a potent pan-inhibitor of matrix metalloproteinases [2].
Note that CGS-27023A imay be used experimentally as the hydrochloride salt (PubChem CID 9888897).
Database Links
ChEMBL Ligand CHEMBL267178
GtoPdb PubChem SID 252827503
PubChem CID 446504
RCSB PDB Ligand CGS
Search Google for chemical match using the InChIKey BSIZUMJRKYHEBR-QGZVFWFLSA-N
Search Google for chemicals with the same backbone BSIZUMJRKYHEBR
Search UniChem for chemical match using the InChIKey BSIZUMJRKYHEBR-QGZVFWFLSA-N
Search UniChem for chemicals with the same backbone BSIZUMJRKYHEBR
SynPHARM 82905 (in complex with MMP1)