SCH486757

Ligand id: 8869

Name: SCH486757

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 49.25
Molecular weight 439.12
XLogP 6.04
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(1R,5S)-8-[bis(2-chlorophenyl)methyl]-3-pyrimidin-2-yl-8-azabicyclo[3.2.1]octan-3-ol
Database Links
CAS Registry No. 524019-25-8 (source: PubChem)
PubChem CID 11597355
Search Google for chemical match using the InChIKey MQWMHMZNBGQNMT-LDSCYUJKSA-N
Search Google for chemicals with the same backbone MQWMHMZNBGQNMT
Search UniChem for chemical match using the InChIKey MQWMHMZNBGQNMT-LDSCYUJKSA-N
Search UniChem for chemicals with the same backbone MQWMHMZNBGQNMT
Comments
SCH486757 is a preclinical nociceptin/orphanin FQ peptide (NOP) receptor agonist [1], with cough suppressing (antitussive) activity.