cobalt protoporphyrin IX

Ligand id: 8902

Name: cobalt protoporphyrin IX

Abbreviated name: CoPP

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 100.38
Molecular weight 619.18
XLogP 3.93
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Synonyms
protoporphyrin IX containing Co
Comments
CoPP is reported as an antagonist of the estrogen receptor β [1]. The PubChem identifier for protoporphyrin IX is CID 4971. This is a very similar structure to iron-bound heme, but with the ferrous ion replaced by a cobalt ion.
Database Links
DrugBank Ligand DB02110
GtoPdb PubChem SID 310264683
PubChem CID 4972
Search Google for chemical match using the InChIKey AQTFKGDWFRRIHR-UHFFFAOYSA-L
Search Google for chemicals with the same backbone AQTFKGDWFRRIHR
Search UniChem for chemical match using the InChIKey AQTFKGDWFRRIHR-UHFFFAOYSA-L
Search UniChem for chemicals with the same backbone AQTFKGDWFRRIHR
SynPHARM 83076 (in complex with Rev-Erb-β)