verosudil

Ligand id: 8911

Name: verosudil

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 89.68
Molecular weight 327.1
XLogP 2.38
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-(dimethylamino)-N-(1-oxo-2H-isoquinolin-6-yl)-2-thiophen-3-ylacetamide
International Nonproprietary Names
INN number INN
10008 verosudil
Synonyms
AR 12286 | AR-12286
Database Links
CAS Registry No. 1414854-42-4
PubChem CID 66906051
Search Google for chemical match using the InChIKey VDYRZXYYQMMFJW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone VDYRZXYYQMMFJW
Search PubMed clinical trials verosudil
Search PubMed titles verosudil
Search PubMed titles/abstracts verosudil
Search UniChem for chemical match using the InChIKey VDYRZXYYQMMFJW-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone VDYRZXYYQMMFJW
Comments
Verosudil is an investigational Rho kinase inhibitor.
The INN record for verosudil indicates that this is a racemic mixture. We show the chemical structure without stereochemistry to represent the mixture. The (2S)-isomer is represented in PubChem CID 86270580 and the (2R)-isomer is represented in CID 44198631.