LY3023414

Ligand id: 8918

Name: LY3023414

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 78.79
Molecular weight 406.2
XLogP 2.22
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
8-[5-(2-hydroxypropan-2-yl)pyridin-3-yl]-1-[(2S)-2-methoxypropyl]-3-methylimidazo[4,5-c]quinolin-2-one
Synonyms
example 1 [US8440829] | LY-3023414
Database Links
CAS Registry No. 1386874-06-1 (source: PubChem)
PubChem CID 57519748
Search Google for chemical match using the InChIKey ACCFLVVUVBJNGT-AWEZNQCLSA-N
Search Google for chemicals with the same backbone ACCFLVVUVBJNGT
Search UniChem for chemical match using the InChIKey ACCFLVVUVBJNGT-AWEZNQCLSA-N
Search UniChem for chemicals with the same backbone ACCFLVVUVBJNGT
Comments
LY3023414 is a dual inhibitor of phosphoinositide 3-kinase α (PI3Kα) and the serine/threonine kinase mTOR ( mechanistic target of rapamycin) [1], with potential antineoplastic activity.